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Dr. Paul Goodyer

Dr. Paul Goodyer, Associate professor, Department of Pediatrics and Department of Human Genetics and Associate Acting professor in the Department of Experimental Medicine at McGill University, Montreal Children's Hospital, Montréal, Québec. He is also Assistant Physician at the Royal Victoria and Montréal General Hospitals and Acting Director, Division of Pediatric Nephology, Montréal Children's Hospital. His most recent award was the Schering Travelling Fellowship Award presented in 1993. He has over 53 papers in scientific journals and presented the same number of abstracts. Paul has contributed nephrology-related chapters in 8 books and given numerous lectures.

Recent Studies:

• The Function of PAX Genes in Human Kidney Development-1995-1998
• Investigation of D2H Mutations in Cystinuria - 1994-1996
• Regulation of Gene Expression in Human Fetal Kidney-1992-1996
• Natural History of Nephropathy of Type I Diabetes-1992-1997

Armstrong, G., Rowe, P. Orrbine, E., Lior, H., Goodyer, P., McLaine, P. and the CPKDRC SYNSORB-Pk Study Group. 1995. A Phase 1 Trial of SYNSORB-Pk in Preventing Hemolytic-Uremic Syndrome (HUS). ). J. Infect. Dis. 171:1042-1045.

Lin, J.-J., Cybulsky, A.V., Goodyer, P., Kaskel, F.J., and R.N. Fine. 1995. Effect of Insulin-like Growth Factor-I on DNA Synthesis and Epidermal Growth Factor Receptor of Post-ishemic Rat Kidney. 1995. J. Lab. Clin. Med. 125: 724-732.

Goodyer, P., Dehbi, M., Torban, E., Bruening, W., and J. Pelletier. 1995. Repression of the Retinoic Acid Receptor-a Receptor Gene by Wilms Tumour Suppressor Gene Product, wt1. Oncogene, 10: 1125-1129.

Cybulsky, A.V., Goodyer, P. and A.J. McTavish. 1994. Epidermal Growth Factor Activation on Developing Rat Kidney. Am. J. Physiol. 267: F428-F436.

Zhang, X_X., Rozen, R., Hediger, M.A., Goodyer, P., and P. Eydoux. 1994. Assignment of the Gene for Cystinuria (SLC3A1) to Human Chromosome 2p21 by Fluorescence in Situ Hybridization. Genomics 24: 413-414.

Bichet, D. G., Birnbaumer, M., Lonergan, M., Arthus, M.-F., Rosenthal, W., Goodyer, P., et al., Nature and Recurrance of AVPR2 Mutations in X-linked Nephrogenic Diabetes Insipidus. 1994. Am. J. Hum. Gen. 55: 278-286.

Rowe, P.C., McLaine, P.N., Orrbine, E., Lior, H., Wells, G.A., and Canadian Pediatric Kidney Disease Reference Centre. 1993. Diarrhoea in Close Contacts as a Risk Factor for Childhood Haemolytic Uraemic Syndrome. Epidemiol. Infect. 110: 9-16

Rowe, P.C., Orrbine, E., Lior, H., Wells, G.A., P.N. McLaine and Canadian Pediatric Kidney Disease Reference Centre. 1993. A prospective study of exposure to verotoxin-producing Escherichia coli among Canadian children with haemolytic uraemic syndrome. Epidemiol Infect 110:1-7(1993)

Rowe, P.C., Orrbine, E., Wells, G.A., P.N. McLaine and Canadian Pediatric Kidney Disease Reference Centre. 1991. Epidemiology of Hemolytic Uremic Syndrome in Canadian children from 1986-1988. J. Pediatr. 119: 218-24.

Should you have any further questions about the CPKDRC and its current projects, please contact Ms. Elaine Orrbine, Associate Director.