Short-Course Antimicrobial Therapy for Paediatric Respiratory Infection (SAFER)
Despite how common paediatric pneumonia is, the optimal duration of antibiotic treatment for it has not been defined; the Infectious Disease Society of America currently recommends 10 days of treatment for mild pneumonia but they note that this guideline is based on very little evidence. This is an important question to address because determining the proper length of antibiotic treatment for a given condition is extremely important. Giving too few days of antibiotics for an infection is obviously problematic; however, giving too many days of antibiotic can also lead to harm, including more drug side-effects,more antibiotics resistance in the population at large, more disruption of the body's normal bacterial flora, and higher drug costs for families. The goal of this study is to determine whether fewer days of amoxicillin for the treatment of mild paediatric pneumonia.
UPDATE: This study will begin in enrollment in Fall 2016