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Christine Armour photo of Christine Armour
Investigator, CHEO Research Institute
Physician (Clinical Geneticist), Department of Genetics, CHEO
Assistant Professor, Department of Pediatrics, University of Ottawa
Research Practice Areas:
Current Research:
Dr. Armour’s main research activity relates to non-invasive detection of fetal genetic conditions from maternal blood. Using different next generation sequencing techniques we are developing the technology and expertise to screen for fetal aneuploidies, small chromosomal deletions and single gene changes present in the fetus without posing any risk to the pregnancy. We are studying different methodologies as well as the feasibility of clinical translation with the goal of applying the techniques to numerous aspects of prenatal and newborn care. Dr. Armour also collaborates with other researchers in the identification and characterization of rare genetic conditions.
Research Team:
  • Dr. Yanwei Xi - Post-doctoral fellow
Dr. Armour is a Clinical Geneticist at the Children’s Hospital of Eastern Ontario, a Clinical Investigator at the CHEO Research Institute and an Assistant Professor in the Department of Pediatrics at the University of Ottawa. She completed the Royal College of Physician and Surgeons training program in Medical Genetics at the University of Ottawa in 2008, after completing medical school at Queen’s University in 2001. She
also received an MSc in Biochemistry in 1997 from the University of Ottawa. Dr. Armour’s main interest is non-invasive prenatal testing using next generation sequencing from cell free DNA, both current and future uses. She is also engaged in the characterization of rare genetic conditions and genotype-phenotype correlations.
Sample Publications:
Armour CM, Smith A, Hartley T, Chardon JW, Sawyer S, Schwartzentruber J, Hennekam R, Majewski J, Bulman DE, Suri M, Boycott KM. Syndrome disintegration: Exome sequencing reveals that Fitzsimmons syndrome is a co-occurrence of multiple events. Am J Med Genet A 2016; 170(7):1820-1825.
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