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Daniela Pohl photo of Dr. Daniela Pohl
Clinical Investigator, CHEO Research Institute
Pediatric Neurologist, Department of Pediatrics,
Children’s Hospital of Eastern Ontario
Associate Professor, Department of Pediatrics,
University of Ottawa

dpohl@cheo.on.ca
613-737-7600 Ext. 1605
Current Research:
Dr. Pohl continues to advance international knowledge on pediatric demyelinating disorders: CHEO is one of only two Canadian centers recruiting patients for an international trial designed to obtain reliable data for the best treatment of pediatric multiple sclerosis, comparing fingolimod to interferon beta 1a. Dr. Pohl’s past and ongoing research has appeared in more than 50 peer-reviewed journal articles to date, including setting international consensus definitions for the diagnosis of pediatric MS and acute disseminated encephalomyelitis (ADEM) and publishing the first nationwide data on incidence of these conditions.
Biography:
Dr. Pohl obtained her MD and PhD in Germany and completed her pediatric and pediatric neurology residency in 2004 at the Children’s University Hospital in Göttingen, Germany. She worked as a Pediatric Neurologist and Epileptologist at the Swiss Epilepsy Centre in Switzerland and at the Epilepsy Centre Kehl-Kork in Germany before joining CHEO as a Pediatric Neurologist in 2008. Dr. Pohl’s main career focus has been the advancement of clinical care for children with multiple sclerosis, locally, nationally and internationally. For a decade, Dr. Pohl has taught colleagues about MS and other inflammatory demyelinating disorders in childhood.
Achievements:
Steering Committee Member and Chair of the Clinical Subcommittee of the International Pediatric Multiple Sclerosis Study Group (IPMSSG) since 2010
Sample Publications:
Buttle SG, Sell E, Dyment D, Bulusu S, Pohl D. Pointed rhythmic theta waves: a unique EEG pattern in KCNQ2-related neonatal epileptic encephalopathy. Epileptic Disord. 2017 Sep 1;19(3):351-356. doi: 10.1684/epd.2017.0927. PMID:28832002

Tardieu M, Banwell B, Wolinsky JS, Pohl D, Krupp LB. Consensus definitions for pediatric MS and other demyelinating disorders in childhood. Neurology. 2016 Aug 30;87(9 Suppl 2):S8-S11. doi: 10.1212/WNL.0000000000002877. Review. PMID:27572866

Waldman A, Ness J, Pohl D, Simone IL, Anlar B, Amato MP, Ghezzi A. Pediatric multiple sclerosis: Clinical features and outcome. Neurology. 2016 Aug 30;87(9 Suppl 2):S74-81. doi: 10.1212/WNL.0000000000003028. Review. PMID:27572865


Pohl D, Alper G, Van Haren K, Kornberg AJ, Lucchinetti CF, Tenembaum S, Belman AL. Acute disseminated encephalomyelitis: Updates on an inflammatory CNS syndrome. Neurology. 2016 Aug 30;87(9 Suppl 2):S38-45. doi: 10.1212/WNL.0000000000002825. Review. PMID:27572859

Wassmer E, Chitnis T, Pohl D, Amato MP, Banwell B, Ghezzi A, Hintzen RQ, Krupp LB, Makhani N, Rostásy K, Tardieu M, Tenembaum S, Waldman A, Waubant E, Kornberg AJ. International Pediatric MS Study Group Global Members Symposium report. Neurology. 2016 Aug 30;87(9 Suppl 2):S110-6. doi: 10.1212/WNL.0000000000002880. Review. PMID:27572855

Chitnis T, Ghezzi A, Bajer-Kornek B, Boyko A, Giovannoni G, Pohl D. Pediatric multiple sclerosis: Escalation and emerging treatments. Neurology. 2016 Aug 30;87(9 Suppl 2):S103-9. doi: 10.1212/WNL.0000000000002884. Review. PMID: 27572854

Thulasirajah S, Pohl D, Davila-Acosta J, Venkateswaran S. Myelin Oligodendrocyte Glycoprotein-Associated Pediatric Central Nervous System Demyelination: Clinical Course, Neuroimaging Findings, and Response to Therapy. Neuropediatrics. 2016 Aug;47(4):245-52. doi: 10.1055/s-0036-1583184. Epub 2016 Apr 29. PMID:27128728

Krupp LB, Pohl D, Ghezzi A, Boyko A, Tenembaum S, Chen L, Aycardi E, Banwell B; REPLAY Study Group. Subcutaneous interferon β-1a in pediatric patients with multiple sclerosis: Regional differences in clinical features, disease management, and treatment outcomes in an international retrospective study. J Neurol Sci. 2016 Apr 15;363:33-8. doi: 10.1016/j.jns.2016.01.023. Epub 2016 Jan 15. PMID:27000217

Luco SM, Pohl D, Sell E, Wagner JD, Dyment DA, Daoud H. Case report of novel DYRK1A mutations in 2 individuals with syndromic intellectual disability and a review of the literature. BMC Med Genet. 2016 Feb 27;17:15. doi: 10.1186/s12881-016-0276-4. Review. PMID:26922654

Tenembaum SN, Banwell B, Pohl D, Krupp LB, Boyko A, Meinel M, Lehr L, Rocak S, Cantogno EV, Moraga MS, Ghezzi A; REPLAY Study Group. Subcutaneous interferon Beta-1a in pediatric multiple sclerosis: a retrospective study. J Child Neurol. 2013 Jul;28(7):849-56. doi: 10.1177/0883073813488828. Epub 2013 May 10. PMID:23666046

Pohl D, Benseler S. Systemic inflammatory and autoimmune disorders. Handb Clin Neurol. 2013;112:1243-52. doi: 10.1016/B978-0-444-52910-7.00047-7. Review PMID:23622335
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