CHEO Research Institute Logo
Decrease Text SizeIncrease Text SizeFacebookTwitterYoutube

researchers working in a lab

Andrée-Anne Ledoux photo of Andrée-Anne Ledoux
Investigator, CHEO Research Institute

aledoux@cheo.on.ca
613-737-7600 Ext. 4104
Research Practice Areas:
Current Research:
Andree-Anne Ledoux's primary area of study is The Pediatric Assessment of Rest and Exertion with MRI (PedCARE+MRI). This study seeks to determine—using state of the art magnetic resonance imaging technology—if early resumption of non-contact physical activity following concussion can restore and improve brain structure and function in patients. This study will provide objective, neurophysiological evidence to be used by health professionals when recommending the best timing to safely reintroduce physical activity after a concussion.
Research Team:
  • Katherine Healy - Research Assistant, Trainee
Biography:
Dr. Ledoux, earned her PhD studies in Experimental Psychology at the University of Ottawa, specializing in behavioural neuroscience and neuropsychology. She was the recipient of the Frederick Banting and Charles Best Canada Graduate Scholarships for her master and PhD studies. Her research interest includes the development of novel approaches for the assessment, treatment and understanding of concussion, neurocognitive and mental health. She has published in the areas of neuroimaging and schizophrenia, virtual reality paradigms, and concussion. Currently, she is investigating how early resumption of physical activity influences the clinical, neurophysiological and neurocognitive recovery in concussed children. Neuroscience is cool!
Sample Publications:
Ledoux, A-A., Barrowman, N., Boutis, K., Davis, A., Reid, S., Sangha, G., Farion, K.J., Belanger, K., Tremblay, M.S., Yeates, K.O., DeMatteo, C., Reed, N., Zemek, R. (2017). Multicentre, Randomized Clinical Trial of Pediatric Concussion Assessment of Rest and Exertion (PedCARE): A Study to Determine When to Resume Physical Activities Following Concussion in Children. British Journal of Sport Medecine.

Grool, A, Aglipay, M., Momoli, F., Meehan III, W., Freedman, S., Yeates, K.O., Gravel, J., Gagnon, I., Bouttis, K., Meeuwisse, W., Barrowman, N., Ledoux, A-A., Osmond, M.H. & Zemek, R. (2016). Association Between Early Participation in Physical Activity Following Acute Concussion and Persistent Post-Concussive Symptoms in Children and Adolescents, JAMA, 316(23): 2504-2514.

Novak, Z., Aglipay, M., Barrowmna, N., Yeates, K.O., Beauchamp, M.H., Gravel, J., Freedman, S.B., Gagnon, I., Gioia, G., Boutis, K., Burns, E., Ledoux,A-A, Osmond, M.H., and Zemek, R (2016). Association of Persistent Postconcussion Symptoms With Pediatric Quality of Life, JAMA: Pediatrics, 170(12): e162900.

Bresee, N., Aglipay, M., Dubrovsky, A.S., Ledoux, A-A., Momoli, F., Gravel, J., Freedman, S., Barlow, K., Richer, L., Barrowman, N., and Zemek, R. (2018) Association between metoclopramide treatment in the ED and post-concussion headache. Emergency Medecine.

Post, A., Hoshiza, T., Gilcrist, M., Koncan, D., Dawson, L., Chen, W., Ledoux, A-A, Zemek, R. (2017). A comparison in a youth population between those with and without a history of concussion using biomechanical reconstruction Journal of Neurosurgery Pediatrics, 27: 1-9.

Post, A., Hoshiza, T., Zemek, R., Gilcrist, M., Koncan, D., Dawson, L., Chen, W., Ledoux, A-A. (2017). Pediatric concussion: Biomechanical differences between transient and PPCS persistent post concussive symptoms (>4 weeks) outcomes, Journal of Neurosurgery Pediatrics, 28(1): 1-11.

Ledoux, A-A., Boyer, P, Phillips, J.L., Labelle, A., Smith, A., Bohbot, V.D. (2015). Structural hippocampal anomalies in a schizophrenia population correlate with navigation performance on a wayfinding task. In Ales Stuchlik and Tomiki Symiyoshi (Eds.) Cognitive Deficits In Schizophrenia and Other Neuropsychiatric Disorders: Convergence of Preclinical and Clinical Evidence (pp. 35-35). (e-Book).

Ledoux, A-A., Boyer, P, Phillips, J.L., Labelle, A., Smith, A., Bohbot, V.D. (2014) Structural hippocampal anomalies in a schizophrenia population correlate with navigation performance on a wayfinding task. Frontiers Behavioral Neuroscience 8(88).

Ledoux, A-A., Phillips, J.L., Labelle, A., Smith, A., Bohbot, V.D., Boyer, P. (2013) Decreased fMRI activity in the hippocampus of patients with schizophrenia tested on a wayfinding task in a virtual town. Psychiatry Research: Neuroimaging, 221(1), 47-56
Take Action
Quick Links

Our Researchmagnifying glass

abcefg hijklmnopqrst uvwxyz