CHEO Research Institute Logo
Decrease Text SizeIncrease Text SizeFacebookTwitterYoutube

researchers working in a lab

Ciarán Duffy photo of Ciarán Duffy
Senior Scientist, CHEO Research Institute
Pediatric Rheumatologist and Clinical Epidemiologist, CHEO
Chief of Pediatrics, CHEO
Professor and Chairman, Department of Paediatrics, CHEO
Faculty of Medicine, University of Ottawa
National Principal Investigator, LEAP Study
National Principal Investigator, REACCH OUT Study

cduffy@cheo.on.ca
613-737-7600 Ext. 2636
Research Practice Areas:
  • Outcomes in juvenile idiopathic arthritis (JIA)
  • Physical activity in juvenile idiopathic arthritis (JIA)
  • Quality of life in juvenile idiopathic arthritis (JIA)
Current Research:
Dr. Duffy is the principal investigator for a national study called “LEAP” (Linking Exercise, Activity and Pathophysiology) in Juvenile Idiopathic Arthritis: A Canadian Collaborative Team, involving 12 pediatric centres. In Canada, juvenile idiopathic arthritis (JIA) afflicts approximately 10,000 children and youth, causing pain, disability and long-term joint and bone damage. The research study aims to uncover the factors specific to children with JIA that affect their ability to participate in physical activities and the barriers to such participation. The study also aims to determine how varying levels of physical activity affect the inflammation of arthritis and its effects on the developing bones and muscles, of children with JIA. Dr. Duffy is also a co-investigator on other national studies involving youth with Juvenile Idiopathic Arthritis (JIA). They include studies which seek to: (1.) gain a rich understanding of how children with JIA and their parents acquire new information on JIA, including the barriers they face when seeking this information, the information they feel is most important and useful to them, and their awareness and attitudes towards research; (2.) develop a web-based, peer support program for teens with JIA; or (3.) gather information on JIA as part of a national registry, which will be used to help rheumatologists better understand and treat JIA.
Research Team:
Biography:
Dr. Duffy is Chief of Pediatrics at CHEO and Professor and Chairman within the Department of Pediatrics, Faculty of Medicine at the University of Ottawa. He was previously Professor and Associate Chairman of the Department of Pediatrics at McGill University and Director of the Division of Rheumatology and Associate Pediatrician-in-Chief at The Montreal Children’s Hospital. After moving to Canada from Ireland, he completed a research/clinical fellowship at The Hospital for Sick Children in Toronto, his pediatric residency at The Children’s Hospital of Western Ontario in London, and a Master’s degree in Science (Clinical Epidemiology and Biostatistics) at McMaster University in Hamilton. He has a wide experience in teaching and is a very active researcher.
Sample Publications:
Rose-Davis B, Curran J, Wright J, Cellucci T, Duffy CM, Tucker LB, Batthish M, Huber AM, Lang B, Levy DM, Rumsey DG, Watanabe Duffy KN, Stringer E. Factors Influencing the Uptake of Canadian Research Findings into the Care of Children with Arthritis: A Healthcare Provider Perspective. J Rheumatol. 2019 Mar;46(3):294-300. doi: 10.3899/jrheum.180282. Epub 2018 Nov 15.

Longmuir PE, Jackson J, Ertel E, Bhatt M, Doja A, Duffy C, Gardin L, Jurencak R, Katz SL, Lai L, Lamontagne C, Lee S, Lougheed J, McCormick A, McMillan HJ, Pohl D, Roth J, Theoret-Douglas C, Watanabe Duffy K, Wong D, Zemek R. Sensitivity, Specificity and Reliability of the Get Active Questionnaire for Identifying Children with Medically Necessary Special Considerations for Physical Activity. Appl Physiol Nutr Metab. 2018 Nov 30. doi: 10.1139/apnm-2018-0314. [Epub ahead of print].

Houghton KM, Macdonald HM, McKay HA, Guzman J, Duffy C, Tucker L; LEAP Study Investigators. Feasibility and safety of a 6-month exercise program to increase bone and muscle strength in children with juvenile idiopathic arthritis. Pediatr Rheumatol Online J. 2018 Oct 22;16(1):67. doi: 10.1186/s12969-018-0283-4.

Lee JJY, Duffy CM, Guzman J, Oen K, Barrowman N, Rosenberg AM, Shiff NJ, Boire G, Stringer E, Spiegel L, Morishita KA, Lang B, Reddy D, Huber AM, Cabral DA, Feldman BM, Yeung RSM, Tucker LB, Watanabe Duffy K; ReACCh-Out Investigators. Prospective Determination of the Incidence and Risk Factors of New-Onset Uveitis in Juvenile Idiopathic Arthritis: The Research in Arthritis in Canadian Children Emphasizing Outcomes Cohort. Arthritis Care Res (Hoboken). 2018 Oct 15. doi: 10.1002/acr.23783. [Epub ahead of print].

Sims-Gould J, Race DL, Macdonald H, Houghton KM, Duffy CM, Tucker LB, McKay HA. "I just want to get better": experiences of children and youth with juvenile idiopathic arthritis in a home-based exercise intervention. Pediatr Rheumatol Online J. 2018 Sep 20;16(1):59. doi: 10.1186/s12969-018-0273-6.

Shiff NJ, Tupper S, Oen K, Guzman J, Lim H, Lee CH, Bryce R, Huber AM, Boire G, Dancey P, Feldman B, Laxer R, Miettunen P, Schmeling H, Watanabe Duffy K, Levy DM, Turvey S, Bolaria R, Bruns A, Cabral DA, Campillo S, Chédeville G, Feldman DE, Haddad E, Houghton K, Johnson N, Jurencak R, Lang B, Larche M, Morishita K, Ramsey S, Roth J, Schneider R, Scuccimarri R, Spiegel L, Stringer E, Tse SM, Yeung R, Duffy CM, Tucker LB. Trajectories of pain severity in juvenile idiopathic arthritis: results from the Research in Arthritis in Canadian Children Emphasizing Outcomes cohort. Pain. 2018. 159(1):57-66.

Oen K, Guzman J, Dufault B, Tucker LB, Shiff NJ, Duffy KW, Lee JJY, Feldman BM, Berard RA, Dancey P, Huber AM, Scuccimarri R, Cabral DA, Morishita KA, Ramsey SE, Rosenberg AM, Boire G, Benseler SM, Lang B, Houghton K, Miettunen PM, Chédeville G, Levy DM, Bruns A, Schmeling H, Haddad E, Yeung RSM, Duffy CM; the Research in Arthritis in Canadian Children emphasizing Outcomes (ReACCh-Out) investigators. Health-Related Quality of Life in an Inception Cohort of Children With Juvenile Idiopathic Arthritis: A Longitudinal Analysis. Arthritis Care Res (Hoboken). 2018 Jan;70(1):134-144. doi: 10.1002/acr.23236. Epub 2017 Dec 6.

McMillan HJ, Jansen GH, Koujok K, Milman N, Duffy CM, Watanabe Duffy K. Mononeuritis multiplex associated with minocycline in an adolescent. Muscle Nerve. 2017 Oct;56(4):E33-E35. doi: 10.1002/mus.25718. Epub 2017 Jun 19.
 
Guzman J, Kerr T, Ward LM, Ma J, Oen K, Rosenberg AM, Feldman BM, Boire G, Houghton K, Dancey P, Scuccimarri R, Bruns A, Huber AM, Watanabe Duffy K, Shiff NJ, Berard RA, Levy DM, Stringer E, Morishita K, Johnson N, Cabral DA, Larché M, Petty RE, Laxer RM, Silverman E, Miettunen P, Chetaille AL, Haddad E, Spiegel L, Turvey SE, Schmeling H, Lang B, Ellsworth J, Ramsey SE, Roth J, Campillo S, Benseler S, Chédeville G, Schneider R, Tse SML, Bolaria R, Gross K, Feldman D, Cameron B, Jurencak R, Dorval J, LeBlanc C, St Cyr C, Gibbon M, Yeung RSM, Duffy CM, Tucker LB. Growth and weight gain in children with juvenile idiopathic arthritis: results from the ReACCh-Out cohort. Pediatr Rheumatol Online J. 2017 Aug 22;15(1):68. doi: 10.1186/s12969-017-0196-7.

Guzman J, Oen K, Huber AM, Watanabe Duffy K, Boire G, Shiff N, Berard RA, Levy DM, Stringer E, Scuccimarri R, Morishita K, Johnson N, Cabral DA, Rosenberg AM, Larché M, Dancey P, Petty RE, Laxer RM, Silverman E, Miettunen P, Chetaille AL, Haddad E, Houghton K, Spiegel L, Turvey SE, Schmeling H, Lang B, Ellsworth J, Ramsey SE, Bruns A, Roth J, Campillo S, Benseler S, Chédeville G, Schneider R, Tse SM, Bolaria R, Gross K, Feldman B, Feldman D, Cameron B, Jurencak R, Dorval J, LeBlanc C, St Cyr C, Gibbon M, Yeung RS, Duffy CM, Tucker LB; ReACCh-Out investigators. The Risk and Nature of Flares in Juvenile Idiopathic Arthritis: Results from the ReACCh-Out Cohort. Ann Rheum Dis. 2016 Jun;75(6):1092-8. doi: 10.1136/annrheumdis-2014-207164. Epub 2015 May 18.

Race DL, Sims-Gould J, Tucker LB, Duffy CM, Feldman DE, Gibbon M, Houghton KM, Stinson JN, Stringer E, Tse SM, McKay HA. 'It might hurt, but you have to push through the pain': Perspectives on physical activity from children with juvenile idiopathic arthritis and their parents. J Child Health Care. 2016 Dec;20(4):428-436. doi: 10.1177/1367493516632616. Epub 2016 Jul 25.

Guzman J, Oen K, Tucker LB, Huber AM, Shiff N, Boire G, Scuccimarri R, Berard R, Tse SM, Morishita K, Stringer E, Johnson N, Levy DM, Duffy KW, Cabral DA, Rosenberg AM, Larché M, Dancey P, Petty RE, Laxer RM, Silverman E, Miettunen P, Chetaille AL, Haddad E, Houghton K, Spiegel L, Turvey SE, Schmeling H, Lang B, Ellsworth J, Ramsey S, Bruns A, Campillo S, Benseler S, Chédeville G, Schneider R, Yeung R, Duffy CM; for the ReACCh-Out investigators. The Outcomes of Juvenile Idiopathic Arthritis in Children Managed with Contemporary Treatments: Results From the ReACCh-Out Cohort. Ann Rheum Dis. 2015 Oct;74(10):1854-60. doi: 10.1136/annrheumdis-2014-205372. Epub 2014 May 19. 

View Q & A
Take Action
Quick Links

Our Researchmagnifying glass

abcefg hijklmnopqrst uvwxyz