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Jason Brophy Photo of Dr. Jason Brophy
Investigator, CHEO Research Institute
Physician, Division of Infectious Diseases, Department of Pediatrics, CHEO
Medical Director – CHEO HIV Clinic; Physician Lead –
CHEO Congenital Infection Clinic
Associate Professor, Department of Pediatrics,
Faculty of Medicine, University of Ottawa

jbrophy@cheo.on.ca
613-737-7600 Ext. 2651
Research Practice Areas:
Current Research:

HIV Research performed by the CHEO IDeas (Infectious Diseases) Research Unit evaluates issues related to children and HIV infection. Specific project topics include: the epidemiology of pediatric/perinatal HIV and its prevention in Canada; the impact of early antiretroviral treatment on viral reservoirs in children; antiretroviral toxicities in children living with or perinatally exposed to HIV; immunogenicity of routine vaccinations in children living with HIV; and transition of adolescents living with HIV from pediatric to adult care. In addition, Dr. Brophy studies congenital CMV infection and zoonotic / travel-related infections in children.

Research Team:
Biography:

Dr. Jason Brophy is a Clinician Investigator at the CHEO Research Institute and an Associate Professor in the Department of Pediatrics, Faculty of Medicine at the University of Ottawa. He is a specialist in the field of pediatric infectious diseases. Dr. Brophy's main research interest is in pediatric/perinatal HIV, and he has several CIHR-funded multi-centre studies ongoing across Canada, as well as in high HIV prevalence countries. He is also interested in congenital CMV infection and zoonotic & travel-related infections in children. He is the past chair of the Canadian Pediatric AIDS Research Group, and the co-lead of the Clinical Care & Management Core of the CIHR-Canadian HIV Trials Network. He also works part-time as a Pediatric HIV Clinical Advisor with the Clinton Health Access Initiative; his main role at CHAI is in supporting uptake of optimal treatments for children living with HIV in West-Central Africa and South-East Asia.

Sample Publications:
Budd MA, Calli K, Samson L, Bowes J, Hsieh AYY, Forbes JC, Bitnun A, Singer J, Kakkar F, Alimenti A, Maan EJ, Lewis MES, Gentile C, Côté HCF, Brophy JC. Blood Mitochondrial DNA Content in HIV-Exposed Uninfected Children with Autism Spectrum Disorder. Viruses. 2018 Feb 11;10(2). pii: E77. doi: 10.3390/v10020077.

Brophy J, Bitnun A, Alimenti A, Lapointe N, Samson L, Read S, Karatzios C, Dobson S, Moses E, Blitz S, Lipsky NG, Ogilvie G, Walmsley S, Raboud J, Money D; HPV in HIV Study Group. Immunogenicity and Safety of the Quadrivalent Human Papillomavirus Vaccine in Girls Living With HIV. Pediatr Infect Dis J. 2018 Jun;37(6):595-597. doi: 10.1097/INF.0000000000001874.

Brophy JC, Hawkes MT, Mwinjiwa E, Mateyu G, Sodhi SK, Chan AK. Survival Outcomes in a Pediatric Antiretroviral Treatment Cohort in Southern Malawi. PLoS One 2016; 11(11):e0165772.
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