|The Research Ethics Board (REB) is a standing committee of the Children's Hospital of Eastern Ontario. The REB reports to the Board of Trustees through the Hospital Quality and Safety Committee. The Chair of the REB reports administratively to the Vice-President, People, strategy and performance. The Chair of the CHEO REB also represents the hospital at the regional council of University of Ottawa – affiliated hospitals (COREB).
The REB provides independent, multidisciplinary ethics review of research involving humans that is conducted by staff of the Hospital or Research Institute, and any research involving humans identified or recruited at or through CHEO and the CHEO Research Institute. It has the authority to approve, reject, request modifications to, or terminate any proposed or ongoing research. The primary purpose of the REB is to ensure that research under its purview meets the highest ethical and scientific standards. In carrying out its mandate, the REB is guided by the understanding that: 1) children, youth, and families are vulnerable populations that warrant special protections; and 2) obtaining a reliable answer to a scientific question is an outcome to be so valued that individual benefits can often be deferred or relinquished altogether. For these reasons, the standards that apply to research should often exceed those that apply to clinical care in which a practitioner is guided by his / her fiduciary responsibility to protect the best interest of the patient.
The REB adopts as minimal standards the ‘Tri-Council Guidelines on Research with Human Subjects’, the ‘Good Clinical Practice’ (International Conference on Harmonization – E6), and relevant provincial and federal legislation. Accordingly, the REB considers a number of factors in its review of research protocols including: social and scientific merit, the risks and benefits to subjects, subject selection and recruitment, privacy and confidentiality, record keeping, and the consent and assent processes and documents.
Open this hyperlink to see the CHEO REB Terms of Reference dated September 07, 2016
CHEO REB Membership
Current Membership List
Archived Membership Lists
Open this hyperlink to see the December 2016 full list of Research Ethics Board members.
Open this hyperlink to see the June 2016 full list of Research Ethics Board members.
Ontario Cancer Research Ethics Board
Affiliated site FWA Number:
University of Ottawa
University of Ottawa and CHEO REB Affiliation Agreement
Agreement: The University of Ottawa and the Children’s Hospital of Eastern Ontario have entered into an agreement with respect to the ethical review of research conducted by University employees, academic staff, trainees, postdoctoral fellows and students (collectively “University Personnel”):
Multi-site research conducted among University of Ottawa affiliated institution
- Research conducted by University Personnel (“University Research”) at or through the Children’s Hospital and for which the interaction with human subjects occurs only at the hospital and its affiliated sites, need only be reviewed by the CHEO REB. The University will conduct administrative reviews of these research protocols, as necessary.
- University Research conducted at or through the Hospital and for which the interaction with human subjects occurs either partly or completely at the University, must be reviewed and approved by both the CHEO REB and the appropriate University REB. The University review will typically be conducted through the delegated review process following CHEO REB approval. Submissions to both sites can be made concurrently.
The CHEO REB has agreed to accept (but not require) submissions using the common application form developed by the University of Ottawa-affiliated REB’s (Council of REB’s; COREB; http://www.ohri.ca/ohreb/forms.htm). Investigators are required to submit an application to each COREB member facility in which the research would be conducted. The investigator should first submit the protocol for ethics review to the REB responsible for the primary site of the research (i.e., research with children and adolescents would first be reviewed by the CHEO REB). Note: The University of Ottawa-affiliated REB’s have agreed to share with one another information regarding site reviews of protocols.
For all protocols approved by the CHEO REB, University Personnel must comply with the Board’s determinations and, in particular, shall:
- Follow all procedures of the CHEO REB;
- Submit to the authority of the CHEO REB and are subject to CHEO REB requirements, including, without limitation, the requirement to modify or stop the University research at request of the CHEO REB;
- Not proceed with the University research until approved by the CHEO REB, and, if applicable, by the University’s research contracts office.